Functional Maturation during Bovine Granulopoiesis

Stability of a model of human granulopoiesis using continuous maturation.

A class of mathematical models involving a convection-reaction partial differential equation (PDE) is introduced with reference to recovering human granulopoiesis after high dose chemotherapy with stem cell support. The stability properties of the model are addressed by means of numerical investigations and analysis. A simplified model with proliferation rate and mobilization rate independent o...

Cleavage of β-Crystallins During Maturation of Bovine Lens

Results: The identities of the major crystallins and several additional crystallin species missing portions of their Nterminal extensions were identified in the fetal bovine lens. Besides the previously identified form of βB1 missing 15 residues from its N-terminus, forms of βA3 missing 11 and 22 residues were identified. With aging, the βA3 (-22) species became a major protein in the adult bov...

Bovine microRNomics: Implications during oocyte maturation and pathophysiology of endometrium

MicroRNA Expression during Bovine Oocyte Maturation and Fertilization

Successful fertilization and subsequent embryo development rely on complex molecular processes starting with the development of oocyte competence through maturation. MicroRNAs (miRNAs) are small non-coding RNA molecules that function as gene regulators in many biological systems, including the oocyte and embryo. In order to further explore the roles of miRNAs in oocyte maturation, we employed s...

penicillin-streptomycin in the culture medium during in vitro maturation of bovine oocytes affects nuclear maturation and subsequent embryo development

introduction: standard concentrations of antibiotics in culture media are thought to have no detectable toxic effects on the cultured cells. since antibiotics are biologically active substances, the possibility that they interfere to some extent with cellular processes occurring in the cultured cells can not always be totally excluded. this study, therefore, was conducted to assess whether the ...